Molecular Biology of Wilm's Tumour

Neonatal extra-renal Wilm's tumour.

Successful treatment of intracaval and atrial extension of Wilms' tumour by chemotherapy.

A patient presenting with advanced Wilm's tumour was diagnosed as having inferior vena cava involvement with tumour thrombus extending up to the right atrium, and was treated with preoperative chemotherapy (vincristine, actinocymin D, epirubicin). Atrial and inferior vena cava thrombus disappeared and he underwent a successful nephrectomy.

Echocardiographic pattern of right atrial tumour motion.

Propagation of Wilm's tumour to the right atrium was diagnosed by echocardiography. The tumour prolapsed into the right ventricle during each atrial systole. The presence of the tumour and its motion were confirmed by cardiac catheterization, cineangiography, and surgical exploration. Successful resection of the tumour was accomplished. Echocardiography was helpful in detecting the presence of ...

Pattern of solid paediatric malignant neoplasm at Lumhs, Jamshoro, Pakistan.

BACKGROUND To evaluate pattern and frequency of solid malignant tumour in paediatric age group in our region. METHODS A retrospective study of 113 patients, whose surgical biopsies submitted in histopathology section of Pathology department, LUMHS Jamshoro from January 2001 to December 2005. RESULTS Total of 113 cases, 61 male and 52 female children in age group from 4 months to 15 years we...

Wilm's tumour and renal dysplasia: an hypothesis.

The incidence of renal dysplasia in a series of Wilms' tumours is presented. The distribution of such lesions is discussed, together with their course of development and regression. The kidney is regarded as a particularly suitable organ for studying the relation between dysplasia and neoplasia. A schema is suggested for this association with regard to Wilms' tumour.